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Research Blog

Peptide Research: Testing, Stability & Methods

Cited, educational articles on peptide chemistry, HPLC and mass spec testing, stability, storage and research methods. For research use only.

87 articles
Compounds Compound Profiles Thymosin Alpha-1: A 28-Residue Thymic Peptide The acetylated 28-residue peptide from thymosin fraction 5: its sequence, its precursor, in vitro signaling studies, and how it differs from thymosin beta-4 and thymalin. DODaniel Okafor~5 min read Compounds Compound Profiles Pinealon: Glu-Asp-Arg and the Short-Peptide Bioregulator Concept The chemistry of the Glu-Asp-Arg tripeptide, the preclinical work behind it, and why its DNA-binding hypothesis remains unconfirmed. DODaniel Okafor~5 min read Compounds Compound Profiles Epitalon (Epithalon): A Synthetic Tetrapeptide Bioregulator The chemistry of the Ala-Glu-Asp-Gly tetrapeptide, where it came from, and why its cell-culture literature still needs independent replication. DODaniel Okafor~6 min read Compounds Compound Profiles DSIP (Delta Sleep-Inducing Peptide): Structure and Research History DSIP was isolated in 1977, yet its gene and receptor remain unknown. Its structure, discovery history and the challenges of studying it. DODaniel Okafor~5 min read Compounds Compound Profiles Semax: An ACTH(4-10) Analogue Peptide Semax pairs the ACTH(4-7) segment with a Pro-Gly-Pro tail. Its structure, preclinical findings and methionine-related analytical checks explained. DODaniel Okafor~5 min read Compounds Compound Profiles Selank: A Tuftsin-Derived Heptapeptide Selank extends tuftsin with a Pro-Gly-Pro tail. Here is its structure, stability profile and what rodent and in vitro studies report. DODaniel Okafor~5 min read CompoundsPhoto: Lilly_M / Wikimedia Commons, CC BY-SA 3.0 Compound Profiles Melanotan II (MT-2): Structure and Melanocortin Receptor Pharmacology How melanotan II was designed from alpha-MSH, why its lactam ring matters, and how it behaves at melanocortin receptors in cell-based assays. DODaniel Okafor~5 min read CompoundsPhoto: Lilly_M / Wikimedia Commons, CC BY-SA 3.0 Compound Profiles PT-141 (Bremelanotide): A Cyclic Melanocortin Receptor Agonist Sequence, lactam ring chemistry and melanocortin receptor pharmacology of PT-141 (bremelanotide), with notes on cAMP assays and identity testing. DODaniel Okafor~6 min read CompoundsPhoto: Lilly_M / Wikimedia Commons, CC BY-SA 3.0 Compound Profiles CJC-1295 With and Without DAC: What the Difference Is Both CJC-1295 forms share four substitutions on GHRH(1-29); only one carries the albumin-binding DAC. Here is the chemistry and how to tell them apart. DODaniel Okafor~4 min read
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Educational content for research use only. Not for human consumption. Nothing here is medical advice or a claim about safety or efficacy.

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