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Research Blog

Peptide Research: Testing, Stability & Methods

Cited, educational articles on peptide chemistry, HPLC and mass spec testing, stability, storage and research methods. For research use only.

87 articles
Peptide Fundamentals NAD Enzyme Basics: Cofactor Binding, Specificity and Assays A laboratory guide to NAD enzymes: cofactor chemistry, binding-site structure, engineered specificity, biocatalytic cascades, assays and storage. DODaniel Okafor~8 min read Research Use Only RUO Science Peptides: Labels, Literature and Lab Practice How the research use only category shapes peptide work in the laboratory, from labeling and documentation to literature searches that confuse RUO with RuO2. DODaniel Okafor~6 min read CompoundsPhoto: kaibara87 / Wikimedia Commons, CC BY 2.0 Compound Profiles GHRP-6 and Hexarelin: First-Generation Ghrelin Receptor Agonists GHRP-6 found its receptor before ghrelin was known. Its chemistry, hexarelin and GHRP-2, and why selective agonists like ipamorelin followed. DODaniel Okafor~4 min read Compounds Compound Profiles ARA-290 (Cibinetide): An Erythropoietin-Derived Peptide ARA 290 (cibinetide) was designed from erythropoietin's helix B to engage a proposed tissue-protective receptor without erythropoietic activity. DODaniel Okafor~5 min read Compounds Compound Profiles Dihexa: An Angiotensin IV-Derived Research Compound Dihexa is a capped angiotensin IV analog studied for HGF/c-Met activity. Its structure, proposed mechanism and the limits of the preclinical evidence. DODaniel Okafor~5 min read CompoundsPhoto: Millrock / Wikimedia Commons, Public domain Compound Profiles Glutathione: The γ-Glutamyl Tripeptide Antioxidant in Research Glutathione is a γ-linked tripeptide whose cysteine thiol drives its redox chemistry, assay behavior and instability in solution. EMElena Marsh~5 min read CompoundsPhoto: Kjaergaard / Wikimedia Commons Compound Profiles hCG: Why Human Chorionic Gonadotropin Is a Glycoprotein, Not a Peptide hCG is often called a peptide, but it is a glycosylated heterodimer. Its structure explains IU labeling, analytical methods and storage needs. EMElena Marsh~6 min read CompoundsPhoto: Gannu03 / Wikimedia Commons Compound Profiles Oxytocin: Structure of a Cyclic Nonapeptide Hormone How a nine-residue disulfide ring became the first synthetic peptide hormone, and what its chemistry and receptor pharmacology teach researchers. DODaniel Okafor~5 min read CompoundsPhoto: kaibara87 / Wikimedia Commons, CC BY 2.0 Compound Profiles Kisspeptin: KISS1-Derived Peptides and the KISS1R Receptor The KISS1 gene products, their shared RF-amide decapeptide, KISS1R Gq signaling, and what animal studies show about hypothalamic GnRH neurons. DODaniel Okafor~5 min read
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Educational content for research use only. Not for human consumption. Nothing here is medical advice or a claim about safety or efficacy.

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